Quiznetik

Pharmaceutical Technology 2 | Set 2

1. According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?

A. 1%

B. 2%

C. 4%

D. 5%

Correct : C. 4%

2. What is Primogel?

A. Substituted HPMC for direct compression

B. Modified MCC for direct compression

C. Hydrogelling polymer for gel formation

D. Modified starch for disintegration

Correct : D. Modified starch for disintegration

3. Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets?

A. Dicalcium Phosphate

B. Microcrystalline cellulose

C. Starch

D. Lactose

Correct : D. Lactose

4. Which of the following industrial dryer is used to dry tablet granules?

A. Drum Dryer

B. Fluid dryer

C. Spray dryer

D. Freeze Dryer

Correct : B. Fluid dryer

5. A water soluble substance used as coating material in microencapsulation process is:

A. Polyethylene

B. Silicone

C. HEC

D. Paraffin

Correct : C. HEC

6. One of the following is used as a pH dependent controlled release excipient.

A. Carnauba wax

B. HPMC Phthalate

C. Methyl cellulose

D. Glyceryl Monostearate

Correct : B. HPMC Phthalate

7. A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is.

A. HPMC

B. CAP

C. Polyethylene

D. Carnauba wax

Correct : A. HPMC

8. Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in.

A. 0.1N HCl

B. Phosphate buffer

C. water

D. 0.1 M H2SO4

Correct : C. water

9. Durability of a tablet to combined effects of shock and abrasion is evaluated by using.

A. Hardness tester

B. Disintegration test apparatus

C. Friabilator

D. Screw gauge

Correct : C. Friabilator