Quiznetik

Pharmaceutical Technology 2 | Set 1

1. Which one of these is responsible for hardness of tablet?

Correct : C. Both (a) & (b)

2. Crown thickness of the tablet is measured by

Correct : C. Pychnometer

3. Friablilator is operated for _________ revolutions per minute.

Correct : A. 100

4. In dissolution test, flask is maintained at:

Correct : A. 31° C ± 0.5C

5. Enteric coated tablet disintegrate in ____ hrs in simulated intestinal fluid.

Correct : B. 2

6. Separation of tablet in 2 or more distinct layer is

Correct : C. Lamination

7. Capping is prevented by using:

Correct : A. Flat

8. Plating of punch forces is done by:

Correct : A. Chromium

9. Unequal distribution of color is called

Correct : C. Mottling

10. ________ is directly compressible excipient

Correct : A. Spray Dried lactose

11. Sta-Rx-1500 contain ______ % of moisture

Correct : B. 10

12. pH of small intestine is

Correct : D. 7-8

13. Perforated pan is used for

Correct : C. Both (a) & (b)

14. Subcoating is done to

Correct : C. Both (a) & (b)

15. Which one is the example of Opacifier

Correct : A. TiO2

16. Empty capsule has moisture content in the range of

Correct : C. 50-70%

17. Which machine is designed for filling of pellets?

Correct : A. Rotofil

18. Soft gelatin capsule should not contain more than ____ ppm of iron as impurity?

Correct : B. 15

19. Enteric resin used for coating is?

Correct : C. Shellac

20. Base for chewable tablets include

Correct : A. Mannitol

21. Enteric coated tablet disintegrate in

Correct : C. Intestine

22. Not used as tablet glidant:

Correct : B. Starch

23. Rotosort is used for

Correct : A. Sorting filled capsules

24. Hardness of tablet is measured by

Correct : D. All of the above

25. Whiskering (a tablet defect) is observed with the use of _____ punch.

Correct : C. Concave

26. Shells of gelatin capsules is made elastic by adding

Correct : A. Sorbitol

27. A retardant material that forms a hydrophilic matrix in the formulation of matrix tablet

Correct : D. Carnuba Wax

28. How much amount is accepted to dissolve in a dissolution medium in 20 minute at 50 rpm?

Correct : C. Not less than 80%

29. What’s the role of cam tracks in tablet compression machines?

Correct : A. For proper movement of the punches

30. Which tablet compression machine is best for compression of granules?

Correct : C. Rotary Press

31. Low melting point substances causes processing problem in tablets. Identify it.

Correct : C. Sticking

32. Which capsule size number has the maximum capacity?

Correct : D. 000

33. Gelatin and glycerin are used for the preparation of lamellae in a specified ratio. Identify the correct ratio.

Correct : C. 9:1

34. The 000 size capsules can fill the volume of:

Correct : A. 1.36 ml

35. Which of the following material is not used in extrusion?

Correct : A. Wax

36. What is the name of the phase transition that occurs when a solid is converted directly into a gas (without going through the liquid phase)?

Correct : D. Sublimation

37. _______ is used for bulk handling, warehouse storage and transport shipping. The most common form is a palletized unit load that packs tightly into containers.

Correct : B. Tertiary packaging

38. Packaging Testing includes:

Correct : D. All of the above

39. Disadvantages of plastic material in packaging?

Correct : D. Absorption permeable to moisture

40. Iron oxide, magnesium dioxide and chromium dioxide is the composition of ______ colored glass use in pharmaceutical packaging?

Correct : C. Green

41. Treated Soda lime glass is called as:

Correct : B. Type II

42. Powered glass test used for the standardization of which type of glass material:

Correct : B. Type I, III, IV

43. Correct test for standardization of rubber material

Correct : C. Fragmentation test

44. The main aim of package inserts or leaflets is:

Correct : D. All of the above

45. “Blue” color coding is used for which class of pharmaceutical products?

Correct : A. Miotics

46. “Tan” color coding is used for which class of pharmaceutical products?

Correct : D. Anti infectives

47. “Orange” color coding is used for which class of pharmaceutical products?

Correct : A. Antibiotics

48. “Pink” color coding is used for which class of pharmaceutical products?

Correct : C. Steroids

49. Select the equation that gives the rate of drug dissolution from a tablet:

Correct : C. Noyes-Whitney equation

50. How many tablets require for content uniformity test

Correct : C. 30

51. Enteric coated tablet is dissolved in 0.1 N HCl as per I.P.

Correct : B. 120 minutes

52. During compression, entrapped air may lead to:

Correct : A. Capping & lamination

53. Anhydrous lactose has advantage over hydrous lactose.

Correct : B. Absence of milliard reaction

54. If the dose of the drug is inadequate, then it generally requires the following one, to make up its bulk:

Correct : D. Diluents

55. The first and most widely used diluent in tablet formulation is

Correct : B. Lactose

56. Which of the following is a synthetic adhesive?

Correct : A. PVP

57. Which of the following packaging is commonly used for packaging of capsules?

Correct : C. Both

58. Which of the following is used to fill powdered dry solid into soft gelatin capsules?

Correct : A. Accogel

59. Sealing of capsules is achieved by:

Correct : C. 37 °C – 40 °C

60. Find the correct one.

Correct : D. Both A and C are correct

61. Which is a capsule filling machine?

Correct : D. All of the above

62. Iron content of gelatin for hard and soft gelatin capsule:

Correct : D. NMT 15 ppm

63. Gelatin is hydrolysed product:

Correct : D. Collagen

64. Moisture content of capsule is determined by:

Correct : B. Toulene distillation method

65. ____________ treatment is used for the solubility of gelatin.

Correct : B. Formalin

66. Type A gelatin has its isoelectric point in the region of

Correct : B. pH 9.0

67. In capsules, Elancofil and accofil machine is used for

Correct : A. Filling of powder into capsules

68. In capsules, Qualiseal machine is used for:

Correct : B. Filling the liquids into capsules

69. Sulphur dioxide is used for:

Correct : C. To prevent decomposition of gelatin shell

70. Green bones are used for the preparation of gelatin of the type:

Correct : B. Type B

71. Viscosity of gelatin ranges from:

Correct : D. 25-45 millipoise

72. The approximate particle size of microcapsule using solvent evaporation is:

Correct : A. 5-5000 µm

73. Which of the following is a tamper proof dosage form?

Correct : A. Tablet

74. Weight variation limits as per USP for the tablet weight more than 324 mg:

Correct : C. 5%

75. Apparatus 1 as per USP:

Correct : C. Basket

76. What is different in B tooling and D tooling?

Correct : C. Punch and die diameter are different

77. Ratio of methyl paraben and propyl paraben used as preservative in capsule?

Correct : A. 4:1

78. Dispirin is a?

Correct : A. Dispersible tablet

79. For Sugar Coated tablet, the specified disintegration time is:

Correct : A. 60 min.

80. Adhesion of tablet material to die wall is called:

Correct : A. Sticking

81. Which of the following is responsible for sticking?

Correct : A. Excessive moisture

82. Which of the following is not a commercially available Starch product?

Correct : D. Sugar tab

83. Aerosil is used as a:

Correct : A. Glidant

84. Tablets that are placed between cheek and teeth are known as:

Correct : A. Buccal

85. Flow rate of granules from the hopper can be improved by adding:

Correct : B. Glidants

86. The aim of Sub-coating is:

Correct : A. To increase the bulkiness

87. The following ingredients are commonly used as coating agents for film coating except:

Correct : B. Carnuba Wax

88. The Wurster process can be used for:

Correct : A. Coating

89. In tablet formulation, PVP is used mainly as:

Correct : D. Binder

90. Use of cross povidone in tablet formulation:

Correct : B. Disintegrant

91. Use of colloidal silicone dioxide in tablet formulation:

Correct : C. Glidant

92. Boxes and cartons are covered in which type of packaging in pharmaceutical?

Correct : B. Secondary

93. ____________ is the best pharmaceutical packaging film for tablets, capsules, which is taking place of PVC film.

Correct : D. Alu-alu foil

94. Which of the following polymer is widely used in film coating of tablets?

Correct : C. HPMC

95. Lamination is:

Correct : A. Separation of a tablet into two or more distinct layer

96. Seal coat aim is to:

Correct : A. To prevent moisture deposition

97. Which of the following ingredient is used for polishing of sugar coated tablets

Correct : D. Carnauba wax

98. ____________ decreases the bioavailability of tetracycline.

Correct : B. DCP

99. The first stage of wetting on addition of a granulating agent to the powders is characterized by which one of the followings?

Correct : A. Capillary state

100. Larger values of Ky in the Heckel Plot indicate formation of what quality of tablets?

Correct : A. Harder tablets