1. Hard gelatin capsule contains ______% of moisture
Correct : A. 13-16%
2. Protien constituent of gelatin is type of amino acid
Correct : D. both b&c
3. Nanocapsules have size less than
Correct : A. 1-20um
4. Official anhydrous water miscible ointment bases i.e emulsifying ointment contains
Correct : C. anionic emulsifier
5. Polyethylene glycol is also called as
Correct : C. both a&b
6. What is bloom strength of hard gelatin shell.
Correct : B. 220-280 g
7. Source of rae material derived from cown can be gelatin
Correct : D. both a&b
8. The largest size of capsule is
Correct : D. 0
9. Obaka automatic capsule filler capable of filling up to_____capsule/hour
Correct : C. 165000
10. Hazing of the film is also called as
Correct : D. botha&c
11. Spanules are
Correct : C. hard gelatin capsule filled with coated granules or bed
12. Nanocapsules have size less than
Correct : A. 1-20um
13. the first digit in the propellent number represent
Correct : B. no.of carbon atom
14. The Exveka KEA is
Correct : D. dedusting and polishing machine of capsule
15. ____element in regularly given to modify the solubility of gelatin capsule
Correct : B. formaline
16. Isoelectric point of type A gelatin is______
Correct : A. 4.8-5
17. 7-9 is isoelectric point of
Correct : B. type b
18. Dip coating is use for
Correct : B. acid insoluble coating
19. Relative humidity of softgel is
Correct : A. 0.35
20. Tag open cap apparatus for evalution of
Correct : C. flash point
21. Aerosole store at temperature above
Correct : A. 40 c
22. Dip tubes in aerosols are made up of______
Correct : A. polyethylene & polypropylene
23. Which one of the following comes under the category of oleaginous bases
Correct : B. liq.paraffin
24. Hydrous wool fat is a mixture of
Correct : A. 70%w/w wool fat&30%w/w purified water
25. Polyethylene glycol is also called as
Correct : C. both a&b
26. Which of the following is viscous liquid
Correct : B. macrogel 400
27. Simple ointment contains base
Correct : A. oleaginous
28. Liquid paraffin IP has viscosity greater than
Correct : D. all of the above
29. Tragacanth has HLB value
Correct : D. 13.2
30. Sudden increase in solubility of micells forming surfactant above definite tempreture is known as
Correct : B. kraft point
31. Polysorbate 20 inactivates
Correct : C. benzalconium chloride
32. Liquid paraffin shows type of flow
Correct : C. pseudoplastic
33. Protective property of colloid is expressed by
Correct : A. gold no.
34. Unna’s paste is mixture of
Correct : D. zinc oxide,glycerine & gelatin
35. Conductivity test is performed for
Correct : B. o/w emulsion system
36. Bottle method preparation of emulsion used the proportion of fixed oil:water:acacia
Correct : C. 0.08403935185185185
37. ______ is the bactericidal recommended for ophthalmic used
Correct : D. benzalconium chloride
38. The output of a typical rotary machine ranges from --to—suppositories an hour
Correct : A. 3500-6000
39. The displacement factor of boric acid is ____to the cocoa butter
Correct : D. 0.67
40. Cocoa butter suppositories in storage sometime form
Correct : A. a white powder diposite on surface
41. The suppositories should be stored at
Correct : B. 25+30c & 40c
42. Melting point of suppositories base is determined by
Correct : D. none og above
43. The gamma form of cocoa butter melts at
Correct : D. all of the above
44. The melting point of cocoa butter lies between__to__
Correct : A. 86-95f
45. Formula for HLB value is
Correct : D. all of above
46. Polyethylene glycol bases are incompatible with
Correct : D. both a&c
47. Maillard reaction asociated with
Correct : A. diluents
48. Which is the foolowing ingredient use as antiadherent
Correct : A. acrosil
49. Its shows negative heat of solution are
Correct : A. manitol
50. Trade name of microcrystalline cellulose is
Correct : A. avicel
51. Lubricant used in tablet formulation for
Correct : D. both a&b
52. Which of the superdisintegrants are used in tablet formulation
Correct : C. both a&b
53. Thinner the tablet indicates that
Correct : A. hard tablet
54. Which of the following material used in enteric coated tablet
Correct : A. cap
55. Which is the following modified starch
Correct : A. starx-1500
56. Which are the following apparatus used for tablet hardnes testing
Correct : A. monsanto
57. Unit of hardness
Correct : D. kg/sq.cm
58. According to USP type I dissolution apparatus is
Correct : A. basket
59. Which are the following apparatus used for friability testing
Correct : A. roache fribilator
60. According to USP standard limit for friability test is
Correct : A. 0.5-1%
61. According to IP disintegration time for dispersible tablet is
Correct : A. within 3 min in water at 250c + 10c
62. According to std sparingly soluble means
Correct : A. less than 1 part of solvent required for 1 part of solute
63. Seperation of tablet into two or more distinct layer
Correct : B. lamination
64. Unequal distribution of colour on a tablet with dark spot is
Correct : D. both a & b
65. Chipping is the tablet defect in
Correct : A. breaking of tablet edges
66. Which of the following is principal area of preformulation
Correct : A. bulk characterization
67. Which are the form are more stable
Correct : D. entiotrops
68. Which of the following form having less solubility and lesser tendency to change its form during storage
Correct : A. amorphous form
69. Metastable form having tendency to convert into
Correct : B. unstable form
70. Deliquesent materials means
Correct : A. they absorb sufficient amount of moisture b) they absorb moisture
71. Which of the following method used for amount of moisture absorb determination
Correct : A. gravimetry
72. Which of the following ingredient or polymer used in enteric coated tablet and for purpose of are
Correct : C. for resistant to acidic ph
73. Controlled drug delivery system recently been marketed as
Correct : D. all of the above
74. Various types of polymer membrane permeation-controlled drug delivery systems includes
Correct : D. all of the above
75. Following parameters play varying degrees of rate-limiting roles in controlling the release of drug molecules from membrane permeation or matrix diffusion
Correct : D. all of the above
76. The diffusion of small molecules in a polymer structure is an
Correct : A. energy-activated process
77. The controlled release of a drug species from both polymer membrane and polymer matrix controlled drug delivery systems is governed by
Correct : A. ???? fick’s law of diffusion
78. In establishing a good in vitro & in vivo correlation of CDDS following should consider
Correct : D. all of the above
79. Solubilization of poorly soluble drugs in aqueous solution can be effectively accomplished by using
Correct : A. co-solvent systems
80. The effect of partition coefficient on the controlled release of drugs from a matrix type drug delivery device was reported as
Correct : C. both a & b
81. Fillers are often incorporated into polymer to enhance
Correct : B. mechanical strength
82. Both the in-vitro and in-vivo rates of drug release are observed to be dependent on
Correct : C. both a & b
83. One of the materials listed below is most commonly used in film coating of Tablets, Identify.
Correct : A. (a) hydroxypropyl methyl cellulose
84. The loading dose of a drug is usually based on
Correct : D. (d) apparent volume of distribution and desired drug concentration in plasma
85. The characteristics of a good NDDS carrier are:
Correct : D. (d) all of the above
86. Tablet is one of the following forms that an oral drug can take such as
Correct : C. (c)?????? both a & b
87. A wide variety of binders used in tablet dosage form some common one including
Correct : D. (d)?????????? all of the above
88. The hardness of tablets is the principle measurement of
Correct : A. (a) mechanical strength
89. Capsules are made from aqueous solutions of gelling agents like
Correct : D. (d) all the above
90. Vegetable capsules are composed of
Correct : C. (c) both a & b
91. The applicability of Noyes-Whitney equation is to describe
Correct : D. (d) dissolution rate
92. The ability of human eye using illuminated area to detect a particle is limited to
Correct : D. (d) 10 micron
93. Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets?
Correct : D. (d) lactose
94. In which of the following techniques the sample is kept below triple point?
Correct : A. (a) lyophilization???????????????????? ??
95. Drugs in suspensions and semi-solid formulations always degrade by
Correct : C. (c) zero order kinetics????????????????
96. Modified release drug delivery systems may be divided conveniently in to following categories
Correct : C. (c) both a & b
97. According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?