Quiznetik

Pharmaceutics | Set 1

1. Hard gelatin capsule contains ______% of moisture

Correct : A. 13-16%

2. Protien constituent of gelatin is type of amino acid

Correct : D. both b&c

3. Nanocapsules have size less than

Correct : A. 1-20um

4. Official anhydrous water miscible ointment bases i.e emulsifying ointment contains

Correct : C. anionic emulsifier

5. Polyethylene glycol is also called as

Correct : C. both a&b

6. What is bloom strength of hard gelatin shell.

Correct : B. 220-280 g

7. Source of rae material derived from cown can be gelatin

Correct : D. both a&b

8. The largest size of capsule is

Correct : D. 0

9. Obaka automatic capsule filler capable of filling up to_____capsule/hour

Correct : C. 165000

10. Hazing of the film is also called as

Correct : D. botha&c

11. Spanules are

Correct : C. hard gelatin capsule filled with coated granules or bed

12. Nanocapsules have size less than

Correct : A. 1-20um

13. the first digit in the propellent number represent

Correct : B. no.of carbon atom

14. The Exveka KEA is

Correct : D. dedusting and polishing machine of capsule

15. ____element in regularly given to modify the solubility of gelatin capsule

Correct : B. formaline

16. Isoelectric point of type A gelatin is______

Correct : A. 4.8-5

17. 7-9 is isoelectric point of

Correct : B. type b

18. Dip coating is use for

Correct : B. acid insoluble coating

19. Relative humidity of softgel is

Correct : A. 0.35

20. Tag open cap apparatus for evalution of

Correct : C. flash point

21. Aerosole store at temperature above

Correct : A. 40 c

22. Dip tubes in aerosols are made up of______

Correct : A. polyethylene & polypropylene

23. Which one of the following comes under the category of oleaginous bases

Correct : B. liq.paraffin

24. Hydrous wool fat is a mixture of

Correct : A. 70%w/w wool fat&30%w/w purified water

25. Polyethylene glycol is also called as

Correct : C. both a&b

26. Which of the following is viscous liquid

Correct : B. macrogel 400

27. Simple ointment contains base

Correct : A. oleaginous

28. Liquid paraffin IP has viscosity greater than

Correct : D. all of the above

29. Tragacanth has HLB value

Correct : D. 13.2

30. Sudden increase in solubility of micells forming surfactant above definite tempreture is known as

Correct : B. kraft point

31. Polysorbate 20 inactivates

Correct : C. benzalconium chloride

32. Liquid paraffin shows type of flow

Correct : C. pseudoplastic

33. Protective property of colloid is expressed by

Correct : A. gold no.

34. Unna’s paste is mixture of

Correct : D. zinc oxide,glycerine & gelatin

35. Conductivity test is performed for

Correct : B. o/w emulsion system

36. Bottle method preparation of emulsion used the proportion of fixed oil:water:acacia

Correct : C. 0.08403935185185185

37. ______ is the bactericidal recommended for ophthalmic used

Correct : D. benzalconium chloride

38. The output of a typical rotary machine ranges from --to—suppositories an hour

Correct : A. 3500-6000

39. The displacement factor of boric acid is ____to the cocoa butter

Correct : D. 0.67

40. Cocoa butter suppositories in storage sometime form

Correct : A. a white powder diposite on surface

41. The suppositories should be stored at

Correct : B. 25+30c & 40c

42. Melting point of suppositories base is determined by

Correct : D. none og above

43. The gamma form of cocoa butter melts at

Correct : D. all of the above

44. The melting point of cocoa butter lies between__to__

Correct : A. 86-95f

45. Formula for HLB value is

Correct : D. all of above

46. Polyethylene glycol bases are incompatible with

Correct : D. both a&c

47. Maillard reaction asociated with

Correct : A. diluents

48. Which is the foolowing ingredient use as antiadherent

Correct : A. acrosil

49. Its shows negative heat of solution are

Correct : A. manitol

50. Trade name of microcrystalline cellulose is

Correct : A. avicel

51. Lubricant used in tablet formulation for

Correct : D. both a&b

52. Which of the superdisintegrants are used in tablet formulation

Correct : C. both a&b

53. Thinner the tablet indicates that

Correct : A. hard tablet

54. Which of the following material used in enteric coated tablet

Correct : A. cap

55. Which is the following modified starch

Correct : A. starx-1500

56. Which are the following apparatus used for tablet hardnes testing

Correct : A. monsanto

57. Unit of hardness

Correct : D. kg/sq.cm

58. According to USP type I dissolution apparatus is

Correct : A. basket

59. Which are the following apparatus used for friability testing

Correct : A. roache fribilator

60. According to USP standard limit for friability test is

Correct : A. 0.5-1%

61. According to IP disintegration time for dispersible tablet is

Correct : A. within 3 min in water at 250c + 10c

62. According to std sparingly soluble means

Correct : A. less than 1 part of solvent required for 1 part of solute

63. Seperation of tablet into two or more distinct layer

Correct : B. lamination

64. Unequal distribution of colour on a tablet with dark spot is

Correct : D. both a & b

65. Chipping is the tablet defect in

Correct : A. breaking of tablet edges

66. Which of the following is principal area of preformulation

Correct : A. bulk characterization

67. Which are the form are more stable

Correct : D. entiotrops

68. Which of the following form having less solubility and lesser tendency to change its form during storage

Correct : A. amorphous form

69. Metastable form having tendency to convert into

Correct : B. unstable form

70. Deliquesent materials means

Correct : A. they absorb sufficient amount of moisture b) they absorb moisture

71. Which of the following method used for amount of moisture absorb determination

Correct : A. gravimetry

72. Which of the following ingredient or polymer used in enteric coated tablet and for purpose of are

Correct : C. for resistant to acidic ph

73. Controlled drug delivery system recently been marketed as

Correct : D. all of the above

74. Various types of polymer membrane permeation-controlled drug delivery systems includes

Correct : D. all of the above

75. Following parameters play varying degrees of rate-limiting roles in controlling the release of drug molecules from membrane permeation or matrix diffusion

Correct : D. all of the above

76. The diffusion of small molecules in a polymer structure is an

Correct : A. energy-activated process

77. The controlled release of a drug species from both polymer membrane and polymer matrix controlled drug delivery systems is governed by

Correct : A. ???? fick’s law of diffusion

78. In establishing a good in vitro & in vivo correlation of CDDS following should consider

Correct : D. all of the above

79. Solubilization of poorly soluble drugs in aqueous solution can be effectively accomplished by using

Correct : A. co-solvent systems

80. The effect of partition coefficient on the controlled release of drugs from a matrix type drug delivery device was reported as

Correct : C. both a & b

81. Fillers are often incorporated into polymer to enhance

Correct : B. mechanical strength

82. Both the in-vitro and in-vivo rates of drug release are observed to be dependent on

Correct : C. both a & b

83. One of the materials listed below is most commonly used in film coating of Tablets, Identify.

Correct : A. (a) hydroxypropyl methyl cellulose

84. The loading dose of a drug is usually based on

Correct : D. (d) apparent volume of distribution and desired drug concentration in plasma

85. The characteristics of a good NDDS carrier are:

Correct : D. (d) all of the above

86. Tablet is one of the following forms that an oral drug can take such as

Correct : C. (c)?????? both a & b

87. A wide variety of binders used in tablet dosage form some common one including

Correct : D. (d)?????????? all of the above

88. The hardness of tablets is the principle measurement of

Correct : A. (a) mechanical strength

89. Capsules are made from aqueous solutions of gelling agents like

Correct : D. (d) all the above

90. Vegetable capsules are composed of

Correct : C. (c) both a & b

91. The applicability of Noyes-Whitney equation is to describe

Correct : D. (d) dissolution rate

92. The ability of human eye using illuminated area to detect a particle is limited to

Correct : D. (d) 10 micron

93. Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets?

Correct : D. (d) lactose

94. In which of the following techniques the sample is kept below triple point?

Correct : A. (a) lyophilization???????????????????? ??

95. Drugs in suspensions and semi-solid formulations always degrade by

Correct : C. (c) zero order kinetics????????????????

96. Modified release drug delivery systems may be divided conveniently in to following categories

Correct : C. (c) both a & b

97. According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?

Correct : A. (a)???? 1%??????