Quiznetik
Digestion | Set 2
1. Chemotrypsinogen in pancreatic juice is activated by:
A. Enterokinase
B. Alkaline PH
C. Trypsin
D. Bile salts
Correct : C. Trypsin
2. Pancreatic lipase is activated by:
A. gastrin
B. Bile salts
C. Enterokinase
D. none
Correct : B. Bile salts
3. All of the following statements concerning pancreatic secretion are true except:
A. Its pH is about 8
B. Has high HCO₃⁻ content
C. It’s secretion is primarily under neural control
D. Contains digestive enzymes
Correct : C. It’s secretion is primarily under neural control
4. The following stimulate pancreatic secretion rich in enzymes and poor in HCO₃⁻ except:
A. CCK
B. Gatrin
C. Secretin
D. Vagal stimulation
Correct : C. Secretin
5. Loss of pancreatic secretion produces the following except:
A. Maldigestion
B. Malabsorption
C. Dehydration
D. Alkalosis
Correct : D. Alkalosis
6. Pancreatic amylase is activated by:
A. Bile salts
B. Trypsin
C. Cl ⁻ ions
D. Enterokinase
Correct : C. Cl ⁻ ions
7. PH of pancreatic secretion is about:
A. 1
B. 6.5- 7.5
C. 8
D. non
Correct : C. 8
8. he volume of pancreatic secretion per day is about:
A. 0.6 L
B. 1.5 L
C. 3 L
D. non
Correct : B. 1.5 L
9. All the following statements concerning pancreatic secretion are true except:
A. Sympathetic stimulation inhibits pancreatic HCO₃⁻ secretion
B. The cephalic phase accounts for about 20 % of secretion after meal
C. Pancreatic HCO3 depresses further release of secretin
D. Contains enzymes which digest polysaccharides to monosaccharides
Correct : D. Contains enzymes which digest polysaccharides to monosaccharides
10. Pancreatic secretion is inhibited by all the followings except:
A. Somatostatin
B. Glucagon
C. Acid in the duodenum
D. Sympathetic stimulation.
Correct : C. Acid in the duodenum
11. All the following statements about pancreatic secretion are true except :
A. The intestinal phase is the main phase of pancreatic secretion .
B. Gastro-pancreatic reflex stimulates pancreatic secretion .
C. Failure of both pancreatic and biliary secretions is needed before steatorrhea develops .
D. none
Correct : C. Failure of both pancreatic and biliary secretions is needed before steatorrhea develops .
12. All the following are correct statements about pancreatic secretion except:
A. HCO3 rich fluid is secreted by ductal cells in response to secretin .
B. Secretion of enzymes by acinar cells occurs in response to CCK.
C. Vagotomy augment secretion of enzymes after meal .
D. none
Correct : C. Vagotomy augment secretion of enzymes after meal .
13. Select a single incorrect answer about pancreatic secretion.
A. Trypsinogen is activated by enterokinase.
B. Chymotrypsinogen is activated by trypsin
C. Pancreatic lipase is activated by alkaline pH.
D. none
Correct : C. Pancreatic lipase is activated by alkaline pH.
14. The following statements about pancreatic secretion are false except:
A. Pancreatic acini contain trypsin.
B. Vagal stimulation produces HCO3 rich juice.
C. The hormone which stimulates enzyme _ rich secretion also causes contraction of gall bladder.
D. none
Correct : C. The hormone which stimulates enzyme _ rich secretion also causes contraction of gall bladder.
15. All the following are true about liver functions except:
A. Liver cells are the only important site for plasma albumin synthesis.
B. Liver cells can store vitamin B12.
C. Liver cells inactivates certain hormones by conjugation.
D. Essential fatty acids are synthesized in liver.
Correct : D. Essential fatty acids are synthesized in liver.
16. All the following statements are correct about liver cells except:
A. They form non essential amino acids.
B. They form hippuric acid by conjugation of benzoate with glycine.
C. They form TPP from vitamin B6.
D. none
Correct : C. They form TPP from vitamin B6.
17. Liver perform the following function except:
A. Haemopoiesis in adults.
B. Formation of about half of body lymph.
C. Formation of bile salts.
D. none
Correct : A. Haemopoiesis in adults.
18. Liver functions include all the followings except:
A. Excretion of bile.
B. Glycogenolysis
C. Glycogenesis.
D. Formation of essential amino acids.
Correct : D. Formation of essential amino acids.
19. The following statements about bile secretion are correct exept:
A. Canalicular secretion represents 75%of bile secretion.
B. Ductular secretion represents 75% of bile secretion.
C. Bile is secreted by both the hepatocytes and cholangiocytes.
D. none
Correct : B. Ductular secretion represents 75% of bile secretion.
20. all the following statement about bile secretion are true except:
A. Bile contain cholesterol and fatty acids.
B. Hepatic bile has lower specific gravity.
C. Gall bladder bile contain less organic constituent than hepatic bile
D. none
Correct : C. Gall bladder bile contain less organic constituent than hepatic bile
21. Gall bladder bile is characterized by all the followings except:
A. It is relatively acidic
B. Darker in color.
C. More inorganic constituent.
D. Higher specific gravity.
Correct : C. More inorganic constituent.
22. The following statement about bile salts are correct except:
A. They are 2 types 1ry&2nd
B. They are Na+ and K+ salts of bile acids conjugated with glucoronic acid.
C. They are actively reabsorbed from the terminal ilium.
D. none
Correct : B. They are Na+ and K+ salts of bile acids conjugated with glucoronic acid.
23. All the follwings are true about bile salt except;
A. 50% of canalicular flow is dependent on bile salts in the enterohepatic circulation.
B. the amount of bill salts in stool is about 0.2-0.4gm/day
C. The total circulating pool of bile salts is 0.2-04gm
D. none
Correct : C. The total circulating pool of bile salts is 0.2-04gm
24. The following are choleretics except:
A. Bile salts.
B. Secretin.
C. Acetylcholine.
D. Bile pigments
Correct : D. Bile pigments
25. Which of the followings has the highest pH:
A. gastric juice.
B. pancreatic juice.
C. hepatic bile.
D. succus entericus.
Correct : C. hepatic bile.
26. Bile secretion contains the following constituents except:
A. Bile salts.
B. Cholesterol.
C. Free bilirubin.
D. Urobilinogen.
Correct : C. Free bilirubin.
27. Bile secretion is stimulated by the following except:
A. Secretion.
B. Bile salts.
C. Sympathetic stimulation.
D. increase blood flow of liver.
Correct : C. Sympathetic stimulation.
28. Bile salts promotes lipid absorption as a result of all the followings except:
A. Emulsifying fat.
B. Formation of micelles.
C. Activation of pancreatic lipase.
D. Non of the above.
Correct : D. Non of the above.
29. The following statements about absorption of bile salts are true except:
A. Active transport occurs in the distal ileum.
B. Removal of distal ileum reduces their absorption.
C. Passive diffusion transport of them.
D. none
Correct : C. Passive diffusion transport of them.
30. Emptying of gall bladder is stimulated by the followings except:
A. Vagal stimulation.
B. Sympathetic stimulation.
C. CCK
D. none
Correct : B. Sympathetic stimulation.
31. The following statements are correct about functions of gall bladder except:
A. The capacity of gall bladder is 20-60 ml.
B. Bile can be concentrated in gall bladder upto 12-20 folds.
C. Secretion of NaHCO3 by gall bladder prevents precipitation of calcium.
D. none
Correct : C. Secretion of NaHCO3 by gall bladder prevents precipitation of calcium.
32. Select the single correct answer about bile pigments:
A. The principal bile pigment is bilivirdin.
B. Free bilirubin is the conjugated bilirubin.
C. Cholebilirubin is the conjugated bilirubin.
D. Urobilinogen is converted into bilirubin by action of bacteria.
Correct : C. Cholebilirubin is the conjugated bilirubin.
33. All the following statements about bile pigments are true except:
A. They are formed from Hb in RECs.
B. In blood bilirubin combines with plasma albumin to form conjugated bilirubin.
C. Mostly urobilinogen passes with feces as stercobilinogen.
D. none
Correct : B. In blood bilirubin combines with plasma albumin to form conjugated bilirubin.
34. Contraction of gallbladder is described by the following statement except:
A. Occur in response to CCK.
B. It is stimulated mainly by acid chyme in duodenum.
C. It is inhibited by atropine.
D. none
Correct : B. It is stimulated mainly by acid chyme in duodenum.
35. All the following are correct statements about liver cells except:
A. They convert amino acids into glucose.
B. They form cholesterol.
C. They release glucose when blood glucose tend to decrease.
D. They are the only site of synthesis of plasma globulins.
Correct : D. They are the only site of synthesis of plasma globulins.
36. The following statements about bile salts are true except:
A. They help digestion and absorption of fat.
B. They have choleretic action.
C. They are actively absorbed from duodenum.
D. none
Correct : C. They are actively absorbed from duodenum.
37. Choose a single incorrect answer about bile salts:
A. Bile salts are secreted as conjugated bile salts by liver.
B. They are converted to 2ry bile salts by action of intestinal bacteria.
C. They help absorption of calcium and iron.
D. Non of the above.
Correct : D. Non of the above.
38. Emptying of GB is inhibited by the followings except:
A. Somatostatin.
B. Sympathetic stimulation.
C. Estrogen.
D. Progesterone.
Correct : C. Estrogen.
39. The following statements about succus entericus are true except:
A. It contains digestive enzymes.
B. Its secretion depends on the amount of chime in small hntestine.
C. It is secreted by intestinal glands.
D. It is released mainly by vagal stimulation.
Correct : D. It is released mainly by vagal stimulation.
40. Succus entericus is inhibited by the followings except:
A. Adrenaline and noradrenaline.
B. Sympathetic stimulation.
C. Prostaglandins
D. endogenous opiates.
Correct : C. Prostaglandins
41. Intestinal proteolysis is caused by the followings except:
A. Trypsin.
B. Carboxypeptidase.
C. Chymotrypsin.
D. Pepsin.
Correct : D. Pepsin.
42. The intestinal brush border help digestion by the followings except:
A. Facilitating movements of intestinal content.
B. Supplying digestive enzymes and special transport system.
C. Increasing surface area of intestinal mucosa
D. none
Correct : A. Facilitating movements of intestinal content.
43. Cholera toxins cause diarrhea by:
A. Activation of calcium activated C1 – channels in the cells of intestinal crypts.
B. Activation of cAMP-activated C1- channels.
C. Activation of both Ca++ activated and cAMP- activated C1- channels.
D. none
Correct : B. Activation of cAMP-activated C1- channels.
44. The volume of succus entericus per day is about:
A. 0.6L.
B. 2L.
C. 3L.
D. none
Correct : B. 2L.
45. Digestion of proteins by succus entericus enzymes includes all the following enzymes except:
A. Aminopeptidase.
B. Carboxypeptidase.
C. Nucleases.
D. Dipeptidase.
Correct : C. Nucleases.
46. Lactase enzyme splits lactose into:
A. Glucose.
B. Glucose and galactose.
C. Glucose and fructose.
D. none
Correct : B. Glucose and galactose.
47. Enteric lipase splits neutral fat into:
A. Fatty acid and glycerol.
B. Fatty acid glycerol and monoglycerides.
C. Monoglycerides.
D. none
Correct : B. Fatty acid glycerol and monoglycerides.
48. The main mechamism of succus entericus secretion is:
A. Vagal stimulation.
B. CCK.
C. Secretin
D. Local axon reflex
Correct : D. Local axon reflex
49. The extracellular enzyme in succus entericus is:
A. Dipeptidase.
B. Entericlipase.
C. Lactase.
D. Enterokinase.
Correct : D. Enterokinase.
50. The followings are true statements about absorption from small intestine except:
A. Fructose is absorbed by facilitated diffusion.
B. Glucose is absorbed by Na+ dependent 2ry active transport.
C. Vit. B12 is absorbed by diffusion
D. none
Correct : C. Vit. B12 is absorbed by diffusion
51. Choose a single incorrect answer about absorption from small intestine:
A. Gastric HCL help iron absorption
B. K+ions are absorped passively.
C. HCO3- ions are absorbed passively.
D. none
Correct : C. HCO3- ions are absorbed passively.
52. The absorptive surface area of small intestineis over:
A. 2.8m
B. 250m2
C. 7m
D. 50m2
Correct : B. 250m2
53. Intestinal motility help absorption from small intestine by all the following except:
A. Increase blood and O2 supply.
B. Increase lymph flow.
C. Increase osmotic pressure.
D. Increase contact of food with mucosa.
Correct : C. Increase osmotic pressure.
54. The following statement about calcium absorption from small intestine are true except:
A. It occurs by active transport.
B. It requires vit. D and parathormone.
C. It occours by passive diffusion from upper small intestine.
D. It is decreased by excess phosphate and oxalate in food.
Correct : C. It occours by passive diffusion from upper small intestine.
55. The following are true statement about fat absorption from small intestine except:
A. It is helped by bile salts.
B. Glycerol and short chain FAs are absorped passively.
C. Deficiency of fat absorption leads to poor absorption of VIT.B complex.
D. Chylomicrons are extruded into Lacteal laterals by exocytosis.
Correct : C. Deficiency of fat absorption leads to poor absorption of VIT.B complex.
56. The transport of glucose across intestinal mucosa is directly dependent Upon the following except:
A. Na concentration in intestinal lumen.
B. Plasma insulin.
C. Inhibitors of energy metabolism.
D. none
Correct : B. Plasma insulin.
57. Absorption of fat soluble vitamins require the following:
A. Bile.
B. Bile and chymotrypsine.
C. Bile and pancreatic amylase.
D. None of the above.
Correct : A. Bile.
58. The major site of absorption of VIT B12 is:
A. Duodenum.
B. Jujenum.
C. Colon.
D. Ileum.
Correct : D. Ileum.
59. The following are true statement about absorption from small intestine except:
A. Hexose are absorped faster than pentose.
B. D amino acids are absorped better than L amino acids.
C. Glucose is absorped faster than fructose.
D. none
Correct : B. D amino acids are absorped better than L amino acids.
60. The amount of water excreted in stool is about:
A. 100mld
B. 0.5Ld
C. 0.4Ld
D. none
Correct : A. 100mld
61. Absorption of Na ions from small intestine occur by the following except:
A. Special Na channel.
B. Cotransported with Cl.
C. Cotrannsported with glucose and amino acids.
D. None of the above.
Correct : D. None of the above.
62. Absorption of Cl- ions from small intestine occur by the following ways except:
A. 2ry active transport.
B. 1 ry active transport.
C. Passive diffusionparacellularly.
D. none
Correct : B. 1 ry active transport.
63. All of the followings are absorped by Na dependent 2ry active transport except:
A. Glucose and galactose.
B. Amino acids.
C. VitaminC
D. VitaminB.12
Correct : D. VitaminB.12
64. The following are true statement about iron absorption from small intestine except:
A. It is actively absorped from duodenum and jejunum.
B. Its absorption is decreased by tannin.
C. Its absorption is helped by vitamin C.
D. It is transported from the brush borderas Fe+3 or heme.
Correct : D. It is transported from the brush borderas Fe+3 or heme.
65. Fructose is absorped from small intestine by :
A. Simple diffusion.
B. Facilitated diffusion.
C. Na+ dependent 2ry active transport.
D. none
Correct : B. Facilitated diffusion.
66. Pentose is absorped from small intestine by:
A. Simple diffusion.
B. Facilitated diffusion.
C. Na+ dependant 2ry active transport.
D. none
Correct : A. Simple diffusion.
67. Whole proteins may be absorped from small intestine by :
A. Pinocytsis.
B. Na+dependant 2ry active transport.
C. Facilitated diffusion.
D. none
Correct : A. Pinocytsis.
68. Vitamin D is absorped from small intestine as the absorption of :
A. Water soluble vitamins.
B. Glycerol.
C. Cholesterol.
D. Short chain fatty acids
Correct : C. Cholesterol.
69. VitaminC is absorped from small intestine by:
A. Passive diffusion.
B. Na+ dependant 2ry active transport.
C. 1ry active transport.
D. none
Correct : B. Na+ dependant 2ry active transport.
70. Peristaltic contractions of small intestine are characterized by all of the followings except:
A. They are myogenic
B. They are due to local axon reflex
C. They are stimulated by gastro-enteric reflex
D. none
Correct : A. They are myogenic
71. The following reflexes inhibit small intestine motility except:
A. Peritoneo-intestinal
B. Reno-intestinal
C. Gastro-ileal.
D. Somato-intestinal.
Correct : C. Gastro-ileal.
72. Rhythmic segmentation of small intestine is characterized by the following except:
A. It is due to local axon reflex.
B. It is myogenic.
C. Its frequency is determined by BER.
D. Its main function is to mix chyme with the digestive juice.
Correct : A. It is due to local axon reflex.
73. Peristaltic waves in the small intestine are characterized by the following statement except:
A. They occur in response to distention of the wall.
B. Can be abolished by local application of coccaine
C. They are controlled primarily by extrinsic innervation
D. none
Correct : C. They are controlled primarily by extrinsic innervation
74. Migration motor complex is characterized by the following except:
A. It starts in the stomach and spread to terminal ilium.
B. Occurs every1-1.5h.
C. It helps digestion of food
D. It prevents duodeno-gastric reflux.
Correct : C. It helps digestion of food
75. Peristaltic rush are characterized by the following except:
A. They are strong peristaltic contraction.
B. They occur normally.
C. they occur when there is intense irritation or distention of the small intestine.
D. They are intiated by reflexes involving the intrinsic and extrinsic nerves.
Correct : B. They occur normally.
76. Small intestine motility is stimulated by the following except:
A. Gastrin
B. CCK
C. Secretin
D. Motilin.
Correct : C. Secretin
77. Small intestine motility is inhibited by the following except:
A. Somatostatin.
B. VIP.
C. Adrenaline
D. Insulin.
Correct : D. Insulin.
78. Motility of small intestine is inhibited by the following except:
A. Intestino-intestinal reflex
B. Vesico-intestinal reflex.
C. Peritoneal irritation
D. Distention of stomach.
Correct : D. Distention of stomach.
79. Large intestinal secretion is stimulated by:
A. Direct stimulation.
B. Local myentric reflex.
C. Para sympathetic stimulation.
D. All of the above.
Correct : D. All of the above.
80. Colonic motility is stimulated by the following except:
A. Gastro-colic reflex.
B. Colono-colic reflex.
C. Duodeno-colic reflex.
D. none
Correct : B. Colono-colic reflex.
81. Emptying at ileocecal region is promoted by:
A. Distenion of cecum
B. Distention of colon.
C. Distention of stomach.
D. Sympathetic reflex.
Correct : C. Distention of stomach.
82. Emptying at ileocecal region is inhibited by:
A. Gastroileal reflex.
B. Gastrin
C. Colonoileal reflex.
D. Distention of terminal ilium.
Correct : C. Colonoileal reflex.
83. Removal of the entire colon would be expected to cause:
A. Megaloblstic anemia.
B. Severe malnutrition.
C. Decrease urinary urobilinogen.
D. Death.
Correct : C. Decrease urinary urobilinogen.
84. The parasympathetic supply of the distal colon is:
A. Pelvic nerve.
B. Vagus nerve
C. The lesser splanchnic nerve.
D. The pudendal nerve.
Correct : A. Pelvic nerve.
85. The external anal sphincter is supplied by:
A. Pelvic nerve.
B. Pudendal nerve.
C. Vagus nerve
D. none
Correct : B. Pudendal nerve.
86. Large intestine secretion is stimulated by:
A. Direct stimulation.
B. Local .myentric reflex.
C. Parasympathetic stimulation.
D. All the above.
Correct : D. All the above.
87. Mass movement in the colon after meal is due to the following except:
A. Gastrocolic reflex
B. Duodenocolic reflex
C. Gastrin hormone.
D. Secretine hormone.
Correct : D. Secretine hormone.
88. Mass movement in the colon would be abolished by:
A. Vagotomy.
B. Sympathectomy.
C. Destruction of the intrinsic nerve plexus.
D. none
Correct : C. Destruction of the intrinsic nerve plexus.
89. The following are true about defecation except:
A. It is initiated by distention of rectum with feces.
B. It is facilitated by micturition reflex.
C. It is under voluntary control in infant.
D. It is inhibited by pain.
Correct : C. It is under voluntary control in infant.
90. Anal mucosa is sensitive to all of the following except:
A. Pain
B. Stretch.
C. Touch
D. Temperature
Correct : B. Stretch.
91. Rectal mucosa is sensitive to:
A. Pain
B. Touch
C. Temperature
D. Stretch
Correct : D. Stretch
92. Resting anal pressure is mainly due to :
A. Tone of external anal sphincter
B. Tone of the internal sphincter.
C. Tone of the puborectalis muscle.
D. none
Correct : B. Tone of the internal sphincter.
93. Fecal continence requires:
A. Intact innervations of anorectal region
B. Sensation of rectum and anal mucosa.
C. Tone of the internal and external anal sphincter
D. All of the above
Correct : D. All of the above