Quiznetik
Microbiology | Set 10
1. Nalidixic acid activity is due to
A. The inhibition of DNA synthesis
B. Inhibition of protein synthesis
C. The inhibition of cell wall synthesis
D. Both b and c
Correct : A. The inhibition of DNA synthesis
2. The best test for the susceptibility of a microorganism to antibiotics and other chemotherapeutic agents:
A. Tube-dilution test
B. Paper-disc test
C. Both a and b
D. None of these
Correct : C. Both a and b
3. The smallest amount of chemotherapeutic agents required to inhibit the growth of the organism in Vitro is known as
A. MIC (minimum inhibitory concentration)
B. Thermal death point (TDP)
C. Death rate
D. None of these
Correct : A. MIC (minimum inhibitory concentration)
4. Clear-zones formation around antibiotic disc is due to
A. Growth of the bacterium surrounding of the disc
B. Lysis of the bacterial cells surrounding the disc
C. The destruction of paper disc (antibiotic)
D. None of these
Correct : B. Lysis of the bacterial cells surrounding the disc
5. Bacitracin is obtained from
A. subtilis b.
B. anthracis
C. B. cereus
D. B. anthracoid
Correct : A. subtilis b.
6. Vancomycin is obtained from
A. Streptococcus species
B. Aspergillus niger
C. Streptomyces orientalis
D. Bacillus anthracis
Correct : C. Streptomyces orientalis
7. â-lactum antibiotics are
A. Penicillin
B. Cephalosporin
C. Both a & b
D. None of these
Correct : C. Both a & b
8. Virus causing mumps is also responsible for
A. Measle
B. Hepatitis A
C. Rabies
D. Variola
Correct : A. Measle
9. Epidemic pleurodynia and myocarditis of new born infants are both caused by
A. Group B cox sack virus
B. Reovirus
C. Polyomavirus
D. Cytomegalovirus
Correct : A. Group B cox sack virus
10. Human papillomavirus causes following tumors:
A. Hepatic carcinoma
B. Cervical cancer
C. Condyloma acuminatum
D. Plantar wart
Correct : A. Hepatic carcinoma
11. Viral infection is caused due to
A. Acute self limited illness
B. No apparent symptoms
C. Chronic infection with persistent viral shedding
D. All of these
Correct : D. All of these
12. Viruses which have teratogenic property are
A. Herpes simplex virus
B. Cytomegalovirus
C. Rubella virus
D. All of these
Correct : D. All of these
13. Kawasaki syndrome is
A. Most prevalent in Japan and Hawaii
B. Patients show rickettsia like bacteria in skin biopsies
C. Strain involved may be propionibacterium
D. All of these
Correct : D. All of these
14. Mode of action of quinolone antibiotics on growing bacteria was thought to be
A. Inhibition of â lactamase
B. Prevention of the cross linking of glycine
C. Inhibition of DNA gyrase
D. Inhibition of reverse transcriptase
Correct : C. Inhibition of DNA gyrase
15. The role that human play in the plague life cycle is
A. Secondary reservoir
B. Primary transmission vector
C. Primary host
D. Accidental intruder in rat flea cycle
Correct : D. Accidental intruder in rat flea cycle
16. Which organism is responsible for causing fever to a man dealing with goats?
A. Trepanema Pallidum
B. M.tuberculosis
C. Clostridium novyl
D. Brucella melitensis
Correct : D. Brucella melitensis
17. The parasite related to ancylostoma duodenale is
A. Wuchereria bancrofti
B. Necatur americanes
C. Loa loa
D. Trichinella spiralis
Correct : B. Necatur americanes
18. Which of the following amoeba does not live in large intestine ?
A. Entamoeba coli
B. Entamoeda histolytica
C. Endolimax nana
D. Entamoeba gingivalis
Correct : D. Entamoeba gingivalis
19. Which of the following is not related to congenital syphilis?
A. Aneurysm
B. Saddle nose
C. Still birth
D. Hutchiso’s teeth
Correct : A. Aneurysm
20. Streptococcus pyogens produce infection –
A. Streptococcal sore throat
B. Acute glomerulo nephritis
C. Rheumatic fever
D. None of these
Correct : A. Streptococcal sore throat
21. Salmonella which can cause prolong septicaemia.
A. Salmonella anetum
B. Salmonella cholerasuis
C. Salmonella typhimurium
D. Salmonella entritidis
Correct : B. Salmonella cholerasuis
22. E.coli produce which type of toxins?
A. Exotoxin
B. Endotoxins
C. Leucocidin
D. Both a and b
Correct : D. Both a and b
23. Main causative organism of gas gangrene is
A. anthrax
B. Clostridium tetani
C. Cl.deficile
D. Cl.perfringens
Correct : D. Cl.perfringens
24. Causative organism of whooping cough is
A. Bordetella pertussis
B. Bordetella parapertussis
C. Bordetella bronchi septica
D. None of these
Correct : A. Bordetella pertussis
25. Pfeiffer phenomenon is related to
A. Vibrio cholerae
B. B.anthrax
C. Rickettsial pox
D. All of these
Correct : A. Vibrio cholerae
26. Diagnostic test for the identification of primary syphilis:
A. VDRL test
B. Treponema pallidum immobilization test
C. Kahn’s test
D. Dark ground microscopic examination
Correct : D. Dark ground microscopic examination
27. Sporadic summer diarrhea may be caused by
A. E.coli
B. Enterobacter
C. Hafnia
D. Serratia
Correct : A. E.coli
28. Biological false reaction in VDRL is related to
A. Lepra bacilli
B. Corynebacterium diphtheria
C. Cl.welchi
D. None of these
Correct : A. Lepra bacilli
29. The best medium for the production of Penicillin is
A. Nutrient agar
B. Corn steep liquor
C. Sulfite waste liquor
D. Whey
Correct : B. Corn steep liquor
30. Industrially important Antibiotic producing organisms shall be isolated by
A. Disk plate method
B. Direct plate method
C. Serial dilution method
D. Crowded plate method
Correct : D. Crowded plate method
31. Industrial alchohol will be produced by using starter culture
A. Top yeast
B. Middle yeast
C. Bottom yeast
D. Feeder yeast
Correct : C. Bottom yeast
32. Pyruvate decarboxylase acetaldehyde + CO2 = This reaction is specially observed in
A. Lactic acid fermentors
B. Ethanol fermentors
C. Algae
D. Plants
Correct : B. Ethanol fermentors
33. The pyruvate, dehydrogenase → multienzyme complex does not occur in
A. Aerobic bacteria
B. Microphilic bacteria
C. Facultative anaerobic bacteria
D. Strictly anaerobic bacteria
Correct : B. Microphilic bacteria
34. A major ingradient of penicillin production media is
A. Corn meal
B. Corn steep liquor
C. Cane steep liquor
D. None of these
Correct : B. Corn steep liquor
35. the outstanding example of traditional microbial fermentation product is
A. Vinegar
B. Penicillin
C. Citric acid
D. Tetracyclin
Correct : A. Vinegar
36. Which of the following involves the formation of nitrate from ammonia
A. Ammonification
B. Denitrification
C. Nitrification
D. Nitrogen fixation
Correct : C. Nitrification
37. First genetically engineered and biotechnologically produced vaccine was against
A. AID
B. Small pox
C. Herpes simplex
D. Hepatitis B.
Correct : B. Small pox
38. one of the standard cloning vector widely used in gene cloning is
A. Ti pasmid
B. EMBL 3
C. pBR 322
D. EMBL 4
Correct : C. pBR 322
39. In alchoholic fermentation, CO2 is evolved during
A. Decarboxylatin of pyruvic acid
B. Formation of acetaldehyde
C. Oxidation of acetaldehyde
D. Both a and b
Correct : D. Both a and b
40. In the industrial production of streptomycin, the secondary metabolite or byproducts is
A. Vitamin – B12
B. Vitamin – C
C. Vitamin – B6
D. Ethanol
Correct : A. Vitamin – B12
41. Tobacco and tea leaves are fermented to give flavour and taste. This type of fermentation is known as
A. Alcohol fermentation
B. Curing
C. Degradation
D. Lactic acid fermentation
Correct : B. Curing
42. Vinegar fermentation involves
A. Yeasts only
B. Yeasts with lactic bacteria
C. Yeasts with acetic acid bacteria
D. Yeasts with butric acid bacteria
Correct : C. Yeasts with acetic acid bacteria
43. Carcinoma refers to
A. Malignant tumours of the connective tissue
B. Malignant tumors of the skin or mucous membrane
C. Malignant tumours of the colon
D. Malignant tumors of the connective tissue
Correct : D. Malignant tumors of the connective tissue
44. By-product of acetone-butanol fermentation include
A. Riboflavin
B. Penicillin
C. Isopropanol
D. All of these
Correct : A. Riboflavin
45. Transgenic animals are for improvement of the quality of
A. Milk
B. Meat
C. Eggs
D. All of the above
Correct : D. All of the above
46. Thermo resistant bacteria are important in the preservation of foods by
A. Freezing
B. Canning
C. Chemicals
D. Irradiation
Correct : B. Canning
47. The fungus used in the industrial production of citric acid:
A. Rhizopus Oryzac
B. Fusarium moniliformae
C. Rhizopus nigricans
D. Aspergillus nigricans
Correct : D. Aspergillus nigricans
48. Penicilin is commercially produced by
A. P.notatum
B. P.chrysogenum
C. P.citrinum
D. P.roquefortii
Correct : B. P.chrysogenum
49. The most commonly used microorganism in alchohol fermentation is
A. A spergilus niger
B. Bacillus subtilis
C. Sacharomyces cerevisiae
D. Escherichia coli
Correct : A. A spergilus niger
50. V itam in B12 can be estimated and determined by using organism
A. Lactobacillus sps
B. Lactobacillus Leichmanni
C. Bacillus subtilis
D. E.Coli
Correct : B. Lactobacillus Leichmanni
51. Batch fermentation is also called
A. Closed system
B. Open system
C. Fed-Batch system
D. Sub-merger system
Correct : A. Closed system
52. To differentiate lactose and non-lactose fermentors the medium used is
A. Mac Conkey’s medium
B. Stuart’s medium
C. Sugar medium
D. Citrate medium
Correct : A. Mac Conkey’s medium
53. The micro-organism useful for fermentation are
A. Bacteria
B. Yeast
C. Fungi
D. None of these
Correct : B. Yeast
54. Industrial microbiology, mainly depends on the phenomenon
A. Pasteurisation
B. Fermentation
C. Vaccination
D. Both b and c
Correct : B. Fermentation
55. Streptokinase is also termed as
A. Fibrionolysin
B. Catalase
C. Coagulase
D. Hyaluronidase
Correct : A. Fibrionolysin
56. Streptokinase is produced by
A. Staphylococcus aureus
B. Streptococcus pneumoniae
C. Str. faecalis
D. Str. pyogenes
Correct : D. Str. pyogenes
57. Large vessel containing all the parts and condition necessary for the growth of desired microorganisms is called
A. Bio reactor
B. Auto reactor
C. Impeller
D. None of these
Correct : A. Bio reactor
58. Basic principle in industrial microbiology is
A. Suitable growth conditions
B. Fermentation
C. Providing aseptic conditions
D. All of these
Correct : B. Fermentation
59. For thorough mixing of medium of medium and inoculum the part of fermentor useful is
A. Shaft
B. Headspace
C. Impeller
D. Sparger
Correct : C. Impeller
60. Infermentor the top portion left without broth is called
A. Shaft
B. Head space
C. Impeller
D. Sparger
Correct : B. Head space
61. Over heating of fermentator during fermentation is controlled by
A. Cooling jacket
B. Steam
C. Cool air
D. None of these
Correct : A. Cooling jacket
62. Antifoam agent is
A. Silicon compound
B. Corn oil
C. Soyabean oil
D. All of these
Correct : D. All of these
63. The capacity of laboratory fermentors is
A. 12–15 liter
B. 2000 gallons
C. 500 liters
D. 10000 gallons
Correct : A. 12–15 liter
64. For the production of ethanol the raw material used is
A. Molasses
B. Cellulose
C. Sulphite waste liquor
D. None of these
Correct : C. Sulphite waste liquor
65. Different methods of strain improvement are
A. Protoplast fusion
B. Recombinant DNA technique
C. Genetic recombination
D. All of these
Correct : D. All of these
66. Protoplasts can be prepared from
A. Gram positive bacteria
B. Gram negative bacteria
C. Both a & b
D. None of these
Correct : B. Gram negative bacteria
67. Upto the product ion of des irab le production in the fermentor is called
A. Upstream process
B. Downstream process
C. Surface fermentation
D. None of these
Correct : B. Downstream process
68. The purification and recovery of the production after fermentation is called
A. Upstream process
B. Downstream process
C. Surface fermentation
D. None of these
Correct : B. Downstream process
69. If the microorganisms are allowed to nutrient medium is called
A. Submerged fermentation
B. Surface fermentation
C. Dual fermentation
D. All of these
Correct : B. Surface fermentation
70. Submerged fermentations are
A. Batch fermentation
B. Continuous fermentation
C. Both a and b
D. None of these
Correct : C. Both a and b
71. Batch fermentation is also called
A. Closed system
B. Open system
C. Fed-batch system
D. None of these
Correct : A. Closed system
72. If more than one microorganism is used to obtain the required product, that type of fermentation is called
A. Batch
B. Continuous
C. Dual
D. Fed-batch
Correct : C. Dual
73. L. lysine is produced from
A. Coryne bacterium glutamicum
B. Corynebacterium sps.
C. Mycobacterium sps.
D. None of these
Correct : A. Coryne bacterium glutamicum
74. Methods used to get immobilized enzymes:
A. Adsorption
B. Encapsulation
C. Covalent bonding
D. All of these
Correct : D. All of these
75. Raw-material used for the production of alcohol is
A. Molasses
B. Starch
C. Sulphite waste water
D. All of these
Correct : D. All of these
76. Microorganisms used for alcohol production
A. Saccharomyces sereviceae
B. Bacillus subtilis
C. Penicillium chrysogenum
D. None of these
Correct : A. Saccharomyces sereviceae
77. For streptomycin production the microorganisms required are
A. Streptomyces griseus
B. Streptomyces niger
C. Saccharomyces cereviceae
D. All of these
Correct : A. Streptomyces griseus
78. The by-product during streptomycin production is
A. Vitamin A
B. Proline
C. Vitamin B12
D. None of these
Correct : C. Vitamin B12
79. For acetic acid production the methods followed are
A. Orleans process
B. Rapid process
C. Submerged process
D. All of these
Correct : D. All of these
80. For amy lase product ion the m icro organism required is
A. subtilis
B. S. cereviceae
C. A. nigar
D. None of these
Correct : A. subtilis
81. Pectinase is industrially produced from
A. S.cereviceae
B. Trichoderma Koningi
C. A. nigar
D. None of these
Correct : C. A. nigar
82. Cellulose are produced from
A. S.cereviceae
B. Trichoderma Koningi
C. A. nigar
D. None of these
Correct : B. Trichoderma Koningi
83. Industrial Production of Vitamin-B12 is from
A. Propionibacterium sps.
B. Pseudomonas sps.
C. Both a and b
D. None of these
Correct : C. Both a and b
84. Clostridium acetobutylicum is used for the production of
A. Acetone - Butanol
B. Ethanol
C. Vitamin-B12
D. None of these
Correct : B. Ethanol
85. In the production of ethanol industrially the yeast used is
A. K.pneumoniae
B. Kluyreromyces fragilis
C. S. cerevisiae
D. Both b and c
Correct : D. Both b and c
86. Citric acid is used as
A. Flavouring agent in food
B. As an antioxident
C. As preservative
D. All of the above
Correct : D. All of the above
87. C itr ic ac id is produced in aerob ic conditions by the fungi
A. Aspergillu
B. Penicillin
C. Mucor
D. All of these
Correct : D. All of these
88. The raw material for citric acid production is
A. Corn
B. Molasses
C. Starch
D. None of these
Correct : A. Corn
89. Aspergillus niger is used generally for the production of
A. Ethanol
B. Penicillin
C. Citric acid
D. Lactic acid
Correct : C. Citric acid
90. In the citric acid production, the pH to be maintained in the fernmenter is
A. 7.0
B. 5.0 to 6.0
C. 8.0 to 9.0
D. 1.0 to 6.0
Correct : B. 5.0 to 6.0
91. The penicillin produced in large scale submerged fermentations are
A. Penicillin-A
B. Penicillin-D
C. Penicillin-G
D. None of these
Correct : C. Penicillin-G
92. The strain of fungi used for the large scale production of penicillin is
A. Penicillium chrysogenum
B. P-notatum
C. Streptomyces Aurecus
D. Saccharomyces sps
Correct : A. Penicillium chrysogenum
93. 6-amino penicillic acid is prepared from penicillin sps by
A. Acylase
B. Punicillin acylase
C. Penicillinone
D. None of these
Correct : B. Punicillin acylase
94. The pH , to be ma inta ined for the production of penicillin is
A. 7.5
B. 6.5
C. 8.0
D. 5.0
Correct : B. 6.5