1. Nuc le ic ac ids are h igh ly charged polymers due to
Correct : A. There is phosphodiester bond between 5’- hydroxyl of one ribose and 3’–hydroxyl of next ribose
2. The best studied example for specialized
transduction is
Correct : C. ë-phage
3. The diagrammatic representation of the
total no. of genes in DNA is
Correct : B. Gene map
4. During specialized transduction
Correct : B. A few no. of genes are transferred
5. The cell donating DNA during transformation is
Correct : B. Exogenate
6. Genetic information transfer DNA to RNA
is called –
Correct : A. Transcriptase
7. The gene transfer occurs by –
Correct : A. Transformation
8. Which of the following is called serum
Hepatitis?
Correct : C. HBV
9. Which of the following was a non-neural
vaccine for rabies?
Correct : A. HEPV
10. Which type of antibodies will associate
in blood cell coagulation?
Correct : C. IgM
11. In a antigen haptens are
Correct : B. Non-immunogenic
12. The antibody that is first formed after
infection is
Correct : B. IgM
13. Antibodies in our body are produced by
Correct : A. B-lymphocyte
14. The points at which crossing over has
taken place between homologus chromosomes are called
Correct : A. Chiasmata
15. How much of globulin is present in human
serum?
Correct : A. 8%
16. The substance wh ich acts as ant imetabolites are called
Correct : C. Inhibitor
17. Enzymes are chemically
Correct : B. Proteins
18. Monoclonal antibodies are produced by
Correct : A. Hybridoma technology
19. First line of body defence is
Correct : B. Unbroken skin
20. What is the strength of the bond between
antigen and antibody?
Correct : B. Avidity
21. Syphillis is caused by
Correct : C. Treponema pallidum
22. Nergibodies produced by rabies virus
show characteristic _____ inner granues
Correct : A. Basophilic
23. The widely used yeast for the production
of single cell protein is
Correct : C. Candida utilis
24. Analysis of protein antigen is by
Correct : C. Western blot
25. Which of the following can provide naturally acquired passive immunity for the new born.
Correct : B. IgG
26. AIDS disease is caused by a virus which
belongs to
Correct : A. Retro virus group
27. Comp lement based agg lut inat ion
reaction is known as
Correct : A. Haem agglutination
28. Reverse transcriptase is an enzyme
involved in the synthesis of
Correct : A. DNA
29. The cellular immune response is mediated
by
Correct : A. B cell
30. The major immunoglobulin present in the
human serum is
Correct : A. IgG
31. Reagenic type antibody is
Correct : D. IgE
32. Blood group antigens are
Correct : B. Isospecific
33. The reaction of soluble antigen with
antibody is known by
Correct : A. Precipitation
34. Interferon is composed of
Correct : B. Lipoprotein
35. Agglutination reaction is strongest with
the immunoglobulin:
Correct : A. IgM
36. The use of monoclonal antibodies is
Correct : A. Immunotherapy
37. Hybridoma technique is used for
Correct : A. Monoclonal antibodies
38. Test used for AIDS is
Correct : B. ELISA
39. Antibody having high valency is
Correct : D. IgM
40. Intensity of attraction between antigen
and antibody molecule is known as
Correct : A. Affiniy
41. Active immunity is induced by
Correct : A. Infection
42. Pasteur developed the vaccines for
Correct : D. All of the above
43. Delayed type of hypersensitivity is seen
in
Correct : B. Contact dermatitis
44. The fo l low ing are used for the
preservation of virus, except
Correct : C. Ether
45. Antibody formation depends on
Correct : D. All of the above
46. Local immunity is important in
Correct : D. All of these
47. Role of magnesium in vaccine is
Correct : B. Stabilizer
48. Immunity is life long following
Correct : C. Measles
49. To prepare vaccine for small pox, the
material used by Edward Jenner is
Correct : C. Cow-pox material
50. During recombination, the strain that donates genetic material frequently with high rate:
Correct : A. Hfr-Strain
51. The character acquired by the cell due to
recombination is
Correct : D. Heritable
52. T-cells are produced from
Correct : B. Thymus
53. Antibodies are produced from
Correct : B. â-cells
54. Incomplete antigens are called
Correct : C. Haptens
55. To be antigen, the chemical molecule
(protein) needs
Correct : C. Both a and b
56. The parts which filter lymph are
Correct : A. Lymph node
57. The primary cells involved in immune
response are
Correct : C. Lymphocytes
58. Plasma cells are the end cells of
Correct : B. β-cells
59. Basophils have receptors for antibodies
Correct : D. IgE
60. Because of denaturat ion, ant igens
become functionless, these are called:
Correct : C. Hidden epitopes
61. Capacity of antigen to breakdown into small fragments eachwith a single epitopic region is known as
Correct : A. Solubility
62. Antigenic specificity is due to
Correct : C. Steric configuration
63. Antibodies are
Correct : B. Glycoproteins
64. General purpose antibody is
Correct : B. IgG
65. Antibody present in colostrums is
Correct : B. IgA
66. Which antibody is called millionaire
molecule?
Correct : B. IgM
67. IgE is discovered by
Correct : A. Ishizaka
68. Antigen-antibody reactions are
Correct : D. Both a and b
69. Serological reactions are useful for
Correct : C. Both a and b
70. For the separation of antigens the method
used is
Correct : A. Immunoelectrophoresis
71. Counter immunoelectrophoresis is useful
for detection of
Correct : A. One antigen/antibody
72. When a particular antigen is mixed with antibody in the presence of an electrolyte at suitable temperature and pH the particles are clumped, this is called:
Correct : B. Agglutination
73. Toxins and viruses can be detected by
Correct : C. Neutralisation
74. Which is most antigenic?
Correct : A. Exotoxin
75. Shick test is used for the detection of
Correct : A. Diphtheria
76. Secondary function of complements are
Correct : C. Both a and b
77. Very effective, less time consuming and
at a time so many samples can be detected by
Correct : A. ELISA
78. â-cells are involved in
Correct : A. Humoral immunity
79. Innate immunity is
Correct : B. Non-specific
80. Innate immunity is developed by
Correct : C. Both a and b
81. Acquired immunity is
Correct : D. All of these
82. Acquired immunity can be developed by
Correct : C. Both a and b
83. Immediate type hypersensitivity reactions
are
Correct : D. All a, b and c
84. Immediate type of hypersensitivity
reactions are mediated by
Correct : B. β-cells
85. Example for cell-mediated immunity are
Correct : D. All of these
86. Mountax reaction is used for detection
of
Correct : A. T
87. All the antibodies produced from a â-cell
are having
Correct : A. Similar specificity
88. Hybridoma formation in hybridoma
technique is from
Correct : A. Spleen cell – Myeloma cell
89. Anthrax vaccine is prepared by
Correct : A. Attenuated bacilli
90. Attenuated, oral poliomyelitis vaccine is
Correct : C. Sabin vaccine
91. Killed, polio vaccine is
Correct : A. Sabin vaccine
92. Measles vaccine is given to children at
the age of
Correct : C. between 9 months and 10 years
93. Pertussis vaccine is
Correct : B. Formalin killed
94. DPT is
Correct : A. Triple vaccine
95. DPT, is used as vaccine for
Correct : D. All of these
96. DPT is given to children at the age of 16-
24 months, as the dose is
Correct : C. Both a and b
97. If more than one kind of immunizing
agent is included in the vaccine, it is
Correct : C. Mixed vaccine
98. Vacc ines are prepared from k i l led
microbes, they are
Correct : A. Inactivated (killed) vaccine
99. Vaccines used against viral infections are
Correct : A. Measles and Mumps vaccine
100. If the microbes used in the vaccine are
obtained from patient, they are