5. Select correct match with respect to lac-operon model ?
Correct : A. Active represser + inducer Inactive repressor
6. In relation of lac operon in E-coli , Which protein is not regulated by the repressor ?
Correct : A. Tryptophan
7. Which is not correct regarding the activity of helicase during DNA replication ?
Correct : C. separates DNA strands
8. Which of the following enzyme is not produced by E. coli during lactose catabolism ?
Correct : C. Lactose dehydrogenase
9. Which is the incorrect statement regarding HGP ?
Correct : A. HGP is an Indian scientific research project
10. Humans have approximately _____ times more genes than E.coli
Correct : D. 50
11. Which of the following is not according to the chargoff’s rule ?
Correct : D. A + T / G + C =1
12. Select the correct answer / answers from the following
1. Ligase :- Joins short segments of DNA together
2. DNA Polymerase :- cuts DNA at specific sequence
3. Helicase :- Breaks the hydrogen bonds between complementary pairs during DNA replication
4. Gyrase : - Joins weak hydrogen bonds between complementary pairs
Correct : C. 1 and 3 are correct, 2 and 4 false
13. DNA replication in eukaryotes is
Correct : B. Bidirectional with many origin
14. Aminoacids lysine, serine and arginine are coded by how many codons ?
Correct : C. 6 codons
15. Which of the following amino acid is coded by 3 codons ?
Correct : D. Isoleucine
16. How many nucleotides make one okazaki segment in eukaryotes ?
Correct : A. 1000-1500
17. Which of the following enzymes help in the process of formation of phosphodiester bond during reverse transcription ?
Correct : D. RNA - dependant DNA polymerase
18. The two strands of a DNA molecule are separted and one of them is analysed for its A + T / G + C ratio, This is found to be 0.2 What is the A + T / G + C ratio of the other strand
Correct : D. 0.2
19. DNA replication in lagging strand of most of the eukaryotic organis ms is
Correct : B. semi conservative but discontinuous
20. How many bases consist in an average gene ?
Correct : B. 3000
21. Match the following using salient features of Human genome project A B
(P) Less than 2 % genome (i) 3 billion nucleotide bases
(Q) Chromosome 1 (ii) 231 genes
(R) Y chromosome (iii) 2968 genes
(S) Human genome (iv) codes for protein
Correct : A. (P - iv) (Q - iii) ( R - ii) ( S - i)
22. State the use of moleculer medicine ?
Correct : D. All the above
23. Among the following which is used for separation of DNA fragments ?
Correct : D. Electrophoresis
24. In Which of the following DNA not directly involved ?
Correct : C. Translation
25. Transcription begins when one of the following enzymes binds to promotor site.
Correct : B. RNA polymerase
26. What dose A & B represent ?
Correct : C. Helicase, Single strand binding protein
27. State the process and mention the labelled protion.
Correct : B. process of Transcription - X-RNA Polymerase- Y-DNA Template- Z- RNA Transcript
28. What do P, Q, R and S regions of t RNA ?
Correct : A. P - Anticodon loop
29. Which state is represent by the above model
Correct : A. Repressed state of lac operon
30. What does X replesent in the above diagram
Correct : A. Released polypeptide chain
31. What does ‘X’ represent
Correct : D. Both A & C
32. Write the codon for the anticodon on the t - RNA
Correct : A. AGU
33. In the genetic code dictionary how many codons are used to code for all the 20 essential amino-acids?
(AIPMT - 2003)
Correct : B. 64
34. What would happen if in a gene encoding polypeptide of 50 aminoacids 25th codon (UAU) is mutated to UAA ? (AIPMT - 2003)
Correct : A. A Polypeptide of 24 aminoacids will be formed
35. Which one of the following triplet codes, is correctly matched with its specificity for an aminoacid in protein synthesis or as ‘start’ or ‘stop’ codon ?
Correct : D. UAC - Tyrosine
36. What does “Lac” refer to in what we call the lac operon ? (AIPMT - 2003)
Correct : A. Lactose
37. The following ratio is generally constant for a given species (AIPMT - 2004)
Correct : C. G + C / A + T
38. During transcription if the nucleotide sequence of the DNA strand that is being coded is ATACG
then the nucleotide sequence in the m RNA would be (AIPMT - 2004)
Correct : C. U A U G C
39. Which one of the following makes use of RNA template to synthesize DNA (AIPMT - 2005)
Correct : C. Reverse transcriptase
40. Protein synthesis is an animal cell occurs (AIPMT - 2005)
Correct : D. on ribosomes present in cytoplasm as well as in mitochondria
41. E coli cells with a mutant z gene of the lac operon cannot grow in medium containing only lactose as
the source of energy because (AIPMT - 2005)
Correct : B. they cannot synthesize functional beta galactosidase
42. Aminoacid Sequence in protein synthesis is decided by the sequence of (AIPMT - 2006)
Correct : C. m RNA
43. Antiparallel strands of a DNA molecule means that (AIPMT - 2006)
Correct : D. The phosphate groups at the start of two DNA strands are is opposite position (Pole).
44. Polysome is formed by (AIPMT - 2008)
Correct : C. several ribosomes attached to a single m RNA
45. Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a “triplet” (AIPMT - 2009)
Correct : D. Nirenberg and Mathai
46. Select the two correct statement out of the four statement given below about “ Lac opern”(AIPMT-2010)
(i) Glucose or galactose may bind with the repressor and inactivate it
(ii) In the absence of lactose the repressor bind with the operator region
(iii) The Z -gene codes for permease
(iv) This was elucidated by Francois Jacob and Jacques Monod
The correct statements are
Correct : C. ii and iv
47. Which one of the following does not follow the central dogma of molecular biology ? (AIPMT - 2010)
Correct : D. HIV
48. The lac opern consists of (AIPMT - 2010)
Correct : C. Two regulatory genes and three structural genes
49. The 31 - 51Phosphodiester linkages inside a potynucleotide chain serve to join AIPMT - 2010)
Correct : C. One nucleotide with another nucleotide
50. Ribosomal RNA is actively synthesized by
Correct : B. nucleolus
51. If one strand of DNA has the nitrogenous base sequence as ATCTG, What would be the
complementary RNA strand Sequence (AIPMT - 2012)
Correct : B. UAGAC
52. Semiconservative DNA replication using 15 N was demonstrated by (AIIMS -1994)
Correct : C. Meselson and stahl
53. In operan concept, the operator gene combines with (AIIMS -1986)
Correct : A. Regulator protein to switch off structural gene transcription
54. Termination of polypeptide chain is brought about by
Correct : B. UAA , UAG and UGA
55. RNA that picks up specific aminoacid from amino acid pool of cytoplasm to carry it to ribosome during protein synthesis is
Correct : A. t RNA
56. Correct sequenceof code transfer during polypeptide formation is (AIIMS -1999)
Correct : A. DNA , mRNA , t RNA and amino acids
57. Best method to determine paternity is
Correct : D. DNA finger printing
58. DNA is copied from m-RNA molecule with help of
Correct : B. Reverse transcriptase
59. Nucleotide arrangement in DNA can be seen by
Correct : A. X - ray crystallography
60. Pneumococcus experiment proved that (AFMC - 1993)
Correct : C. DNA is genetic material
61. A DNA nucletotide chain has A G C T T C G A sequence The nucleotide sequence of other chain would be
Correct : A. T C G A A G C T
62. A functional unit in synthesis of protein is (MPPMT - 1994)
Correct : C. Polysome
63. VNTR is employed for (AMU - 2002)
Correct : B. DNA finger printing
64. Out of 64 codons 61 code for 20 types of aminoacids It is due to (CBSE - 2002)
Correct : B. Degeneracy of genetic code
65. Okazaki fragments are joined by enzyme (Kerala 2005)
Correct : B. DNA ligase
66. Heat killed pathogenic cells and live non pathogenic cells are mixed and injected into Mice
The result would be (Kerala - 2001)
Correct : A. Mice develop disease and die
67. Generally Cockroach is .......... or .......... colored insect, however in tropical regions, they havebeen reported to be .........., .......... and .......... colored.
Correct : B. Brown or Black, Yellow, Red and Green
68. In case of common species of Cockroach, Morphologically which statement is correct ?
Correct : D. The size of male is slightly bigger than female.
69. Head of the Cockroach is formed by the fusion of .......... segments.
Correct : C. two
70. Why head of the Cockroach can move easily in all the directions ?
Correct : A. In Cockroach head and thorax fuse to form Cephalothorax.
71. On the head region of Cockroach .......... pairs of .......... and .......... shaped eyes occur.
Correct : A. One pair, sessile compound and kidney shaped
72. Mouthparts of periplaneta are consist of ..........different types of articulations.
Correct : C. six
73. On the lateral side of alimentary canal of cockroach .......... glands are found.
Correct : B. Salivary
74. Each walking leg of periplaneta is made up of ..........segments.
Correct : A. five
75. A segment attached to the ventral side of the thorax nearer to the body of Cockroach is .......... .
Correct : C. Coxa
76. Walking legs of periplaneta are attached to .......... and divided into .......... segments.
Correct : B. Ventral sternum, Five
77. Third segment of walking leg of Cockroach is.......... .
Correct : C. Femur
78. Fifthe segment of walking leg of Cockroach is .......... .
Correct : B. Tarsus
79. What is the name of second segment of walking leg of Cockroach ?
Correct : D. Trochanter
80. Each abdominal segment of Ccokroach are covered with .......... outer layers .......... plearae.
Correct : C. Two, One
81. Howmany segment are present in an abdomen of the Cockroach ?
Correct : B. Ten
82. In Cockroach which tergum possesses a median groove ?
Correct : A. Tenth
83. Which is the peculiarity of ninenth sternum of maleCockroach ?
Correct : B. A piar of anal cerci is associated with it
84. Which number of sternum is boatshaped in the Cockroach ?
Correct : C. Seventh
85. In Cockroach which segment has female genital opening ?
Correct : D. Eighth
86. Which segment has male genital opening is Cockroach ?
Correct : A. Ninth
87. Which structure is sound receptor in Cockroach ?
Correct : B. Anal cerci
88. Which segments joint to form a genital pouch in female Cockroach ?
Correct : C. Eighth and Nineth
89. The distal segment of walking leg of a Cockroach is .......... ?
Correct : D. Tarsus
90. In which succession the three main layers of the body wall of a Cockroach from outer to Inner side are arraged ?
Correct : B. Cuticle, Epidermis and basement membrane
91. The Epidermis of body wall of the Cockroach is made up of.......... ?
Correct : C. Columnar epithelium
92. In Cockroach how many stuctures named after malpighian are present ?
Correct : B. Two
93. In Cockroach the cavities of foregut and hindgut are lined with .......... .
Correct : C. Cuticle
94. In the alimentary canal of Cockroach the shape of region following the mouth is .......... .
Correct : C. Norrow tubula
95. How many secreting lobes are present in each salivary gland of Cockroach ?
Correct : A. Two
96. In Cockroch .......... on salivary glands and .......... reservoirs are present ?
Correct : C. Two, Four
97. Crop of the Cockroach occurs at .......... in almentary canal.
Correct : A. Posterior end of oesophagu
98. In which of the following regions crop of the Cockroach is located ?
Correct : C. Thorax and abdomen
99. In Cockroach, gizzard is .......... organ and .......... occur inside it.
Correct : B. Muscular, six chitinous teeth
100. Where are sieve like structures present in the alimentary canal of Cockroach ?